�Researchers from Boston University's Slone Epidemiology Center make found that in a given week, over 10 million Americans are pickings opioids, and more than 4 gazillion are taking them regularly (at least five years per hebdomad, for at least four weeks). These findings appear in the August 31 issue of the journal Pain.
Opioids ar commonly administered for the treatment of moderate to severe painful sensation and ar among the most widely prescribed drugs in the United States. While these drugs make an essential role in pain management, there ar concerns about potential shout. Despite these concerns, characteristics of opioid use within the noninstitutionalised US population are non well known, particularly for recent years.
The researchers conducted a telephone survey of randomly selected U.S. households; there were 19,one hundred fifty subjects cured 18 years or older interviewed from February 1998 through September 2006. Information was gathered on all prescription and non-prescription medications taken during the retiring seven days. For each recorded medication, information was obtained on reason for use, type of administration, number of days taken in the week in front the interview, and total duration of the current use.
The researchers found opioids were victimised 'regularly' by 2 percent of those surveyed. An additional 2.9 pct used opioids less frequently. Regular opioid use increased with age, decreased with education stage, and was more common in females and in non-Hispanic whites. The prevalence of regular opioid enjoyment increased over time and was highest in the South Central region of the area. Among regular users, virtually half had been pickings opioids for two or more age and nearly one-fifth had been taking opioids for five days or thirster. There was also a much higher prevalence of other medicinal drug use among regular opioid users compared to nonusers.
According to the researchers, granted the large number of individuals touched, the recent increase in public wellness concern for safe and effective bother management is appropriate. "From this nationally representative telephone set survey, we estimate that more than 4.3 million U.S. adults are taking opioids regularly in any given week," aforementioned lead writer Judith Parsells Kelly of the Slone Epidemiology Center. "The extent and characteristics of opioid use among U.S. adults reflected in this study reinforces the need to strike a rational counterweight between opioid misuse and effective control of chronic pain," she added.
Data collection was supported by interior Slone Epidemiology Center pecuniary resource and data analysis was supported by GlaxoSmithKline.
Source: Michelle Roberts
Boston University
More info
Monday, 1 September 2008
Wednesday, 6 August 2008
Biological father of Madonna's adopted Malawian son has baby boy
LILONGWE, Malawi - Yohane Banda, the biological father of Madonna's adoptive Malawian boy David, has a new child.
The male child was born July 20, and he and his mother, Flora, are doing well, Banda told The Associated Press on Saturday.
"I am over the moon," said Banda, 33, wHO had lost two sons in babyhood to malaria.
Banda married Flora after the death of his wife Marita from childbirth complications shortly afterward the arrival of David on Sept. 25, 2005.
Banda and his aging mother, Asinati Mwale, decided to surrender David to the Home of Hope Orphanage because they could non afford to buy him formula milk after his mother's death.
Madonna, through her Raising Malawi charity, found him at the orphanage and filed for adoption. A Malawi high court judge in May sanctioned the adoption.
Banda said his new logos, who hasn't been named yet, was born at Mchinji District Hospital, the same one where David was.
"We idea of holding this
Kiss and Tell: Rock Legend Gene Simmons
Unlike many john Rock legends, Gene Simmons did not grow up in a base where music filled the halls.
"It was a unruffled household," Simmons said. "I come from a broken home. My father leftfield us when I was 6 or 7 geezerhood old, and my mother worked from sun up until sundown, so there was never any music at home."
Instead, he observed rock 'n' roll music "naturally" by listening to the tuner. Simmons aforementioned the early rock he listened to "crawled into my blood."
Born Chaim Witz in Haifa, Israel, in 1949, Simmons was the only child of his mother, Florence Klein, a holocaust survivor. Simmons and his mother immigrated to the United States when he was 8 years old. They settled in Queens, N.Y., and Chaim adopted a more American-sounding name: Eugene.
Simmons attended Richmond College in New York and graduated with a degree in education. After college he had a number of positions: He was a sixth-grade teacher in New York's Spanish Harlem, an assistant to the editor in chief of Glamour magazine, and a deli cashier.
In 1973, Simmons colonized on his real heat. Along with his friends Peter, Paul and Ace, he formed the band Kiss.
The idea behind the band was that they would "admit no prisoners." While Simmons admits that "we didn't quite know what that meant," the group took on a bold bravado
onstage that made it famous.
"At the beginning, this was a four-headed wolf called 'Kiss' that had the balls to get down up onstage and grab the existence by the scruff of its neck and proclaim. 'You wanted the best, you got the best, the hottest band in the human race,'" Simmons said. "The rally cry, the manifesto, is 'Rock and Roll All Night and Party Every Day' � it's a feel-good manifesto of a party."
Simmons' onstage fictitious character is known as "the Demon," which came from the documentary "Man of a Thousand Faces," about Lon Chaney, a silent film legend.
Simmons resides in Beverly Hills, Calif., with his
For Children With Neurofibromatosis Type 1, Statin Does Not Improve Cognitive Function
�
For children with neurofibromatosis type 1 (NF1), a genetic disorder
that much leads to learning disability, cognitive function is not
improved by the lipid-lowering medication simvastatin, according to an article released on
July 15 in JAMA.
NF1 is characterized by the development of tumors in Schwann cells in
the uneasy system. It is genetically transmitted with an autosomal
dominant normal, which means that it is non linked to sex chromosome,
but only one parent needs to contribute the variant cistron for a child to
develop the disorder.
These tumors hind end be harmless but can buoy also compress nerve cells thus
causing damage. Clinically, the disease symptoms include skin
disorders, problems with small and large social movement skills, and cognitive
disabilities. Some examples of this cognitive handicap include personnel casualty
of visual-spatial skills, nonverbal long-term memory and attention
span.
Statins are a class of drugs soon used in adults to lower
cholesterol. Previously, some studies in mice bear indicated that
therapy with statins could improve some cognitive deficits. To
investigate the potential effects of a specific lipid-lowering medicine, simvastatin, on
the cognitive function of children with neurofibromatosis type 1,
Lianne C. Krab, M.Sc., of Erasmus MC University Medical Center, Sophia
Children's Hospital, Rotterdam, The Netherlands, and colleagues
performed a randomized trial. A total 62 children received simvastatin
or a placebo treatment once daily for 12 weeks.
After the period of treatment, various cognitive tests were performed
to address nonverbal semipermanent memory, attention, and performance on
the prism version task, which measures the adaptation of hand
movements in reply to distortion of a prism glass. No reward was
shown for the test group over the placebo in this obedience. Secondary
outcomes were evaluated as well, including object meeting place scores,
which showed some improvement in the test population. Other measures,
such as attention fluctuation and motor-visual integration showed no
improvement.
The authors conclude that zocor has no effect on the improvement
of cognitive problems developed in victims of von Recklinghausen's disease type 1.
"The negative upshot of this trial suggests that simvastatin should
not
be prescribed to ameliorate the cognitive deficits associated with NF1.
Further studies to evaluate a longer treatment period and whether the
object assembly finding is spurious whitethorn be warranted," they conclude.
Effect of Simvastatin on Cognitive Functioning in Children
With Neurofibromatosis Type 1: A Randomized Controlled Trial
Lianne C. Krab; Arja de Goede-Bolder; Femke K. Aarsen; Saskia M. F.
Pluijm; Marlies J. Bouman; Jos N. van der Geest; Maarten Lequin;
Coriene E. Catsman; Willem Frans M. Arts; Steven A. Kushner; Alcino J.
Silva; Chris I. de Zeeuw; Henri�tte A. Moll; Ype Elgersma
JAMA. 2008;300(3):287-294.
Click Here For Journal
Written by Anna Sophia McKenney
Copyright: Medical News Today
Not to be reproduced without license of Medical News Today
More info
For children with neurofibromatosis type 1 (NF1), a genetic disorder
that much leads to learning disability, cognitive function is not
improved by the lipid-lowering medication simvastatin, according to an article released on
July 15 in JAMA.
NF1 is characterized by the development of tumors in Schwann cells in
the uneasy system. It is genetically transmitted with an autosomal
dominant normal, which means that it is non linked to sex chromosome,
but only one parent needs to contribute the variant cistron for a child to
develop the disorder.
These tumors hind end be harmless but can buoy also compress nerve cells thus
causing damage. Clinically, the disease symptoms include skin
disorders, problems with small and large social movement skills, and cognitive
disabilities. Some examples of this cognitive handicap include personnel casualty
of visual-spatial skills, nonverbal long-term memory and attention
span.
Statins are a class of drugs soon used in adults to lower
cholesterol. Previously, some studies in mice bear indicated that
therapy with statins could improve some cognitive deficits. To
investigate the potential effects of a specific lipid-lowering medicine, simvastatin, on
the cognitive function of children with neurofibromatosis type 1,
Lianne C. Krab, M.Sc., of Erasmus MC University Medical Center, Sophia
Children's Hospital, Rotterdam, The Netherlands, and colleagues
performed a randomized trial. A total 62 children received simvastatin
or a placebo treatment once daily for 12 weeks.
After the period of treatment, various cognitive tests were performed
to address nonverbal semipermanent memory, attention, and performance on
the prism version task, which measures the adaptation of hand
movements in reply to distortion of a prism glass. No reward was
shown for the test group over the placebo in this obedience. Secondary
outcomes were evaluated as well, including object meeting place scores,
which showed some improvement in the test population. Other measures,
such as attention fluctuation and motor-visual integration showed no
improvement.
The authors conclude that zocor has no effect on the improvement
of cognitive problems developed in victims of von Recklinghausen's disease type 1.
"The negative upshot of this trial suggests that simvastatin should
not
be prescribed to ameliorate the cognitive deficits associated with NF1.
Further studies to evaluate a longer treatment period and whether the
object assembly finding is spurious whitethorn be warranted," they conclude.
Effect of Simvastatin on Cognitive Functioning in Children
With Neurofibromatosis Type 1: A Randomized Controlled Trial
Lianne C. Krab; Arja de Goede-Bolder; Femke K. Aarsen; Saskia M. F.
Pluijm; Marlies J. Bouman; Jos N. van der Geest; Maarten Lequin;
Coriene E. Catsman; Willem Frans M. Arts; Steven A. Kushner; Alcino J.
Silva; Chris I. de Zeeuw; Henri�tte A. Moll; Ype Elgersma
JAMA. 2008;300(3):287-294.
Click Here For Journal
Written by Anna Sophia McKenney
Copyright: Medical News Today
Not to be reproduced without license of Medical News Today
More info
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Tuesday, 8 July 2008
The Dandy Warhols stream new album online
will release their sixth album, 'Earth To The Dandy Warhols', on August 18 � but are streaming the album in full online now.
Fans can hear the album on Dandywarhols.com now.
Users who join the band's subscription service, which costs $34.99 (�17.60) to join, can download the album now and will receive a CD copy of the album between now and the album's official release date.
The album is their first for the bands new record label, Beat The World Records. and The Heartbreakers' guitarist Mike Campbell both guest on album track 'Love Song'.
Head to the Dandy Warhols website to hear the album in full now.
Fans can hear the album on Dandywarhols.com now.
Users who join the band's subscription service, which costs $34.99 (�17.60) to join, can download the album now and will receive a CD copy of the album between now and the album's official release date.
The album is their first for the bands new record label, Beat The World Records. and The Heartbreakers' guitarist Mike Campbell both guest on album track 'Love Song'.
Head to the Dandy Warhols website to hear the album in full now.
Friday, 4 July 2008
Passengers
Artist: Passengers
Genre(s):
Dance
Discography:
The Best
Year: 2001
Tracks: 18
Sound Adventure
Year: 1983
Tracks: 17
Cameron Diaz's father dies suddenly
Reports that Cameron Diaz's father died suddenly after a bout of pneumonia have been confirmed by the actress today.
According to US reports, Emilio Diaz, who was 58, recently picked up the flu, which later progressed to pneumonia.
Reports say that he died suddenly despite the fact that he had been in "terrific health" before his recent illness.
Diaz issued a statement saying: "My mom, sister and I are deeply appreciative of the overwhelming outpouring of love and support during this difficult time for us and all of our family."
"My dad was loved by so many people, and his humour and spirit will always live on in our hearts," she said.
Cameron Diaz is currently working on her new film 'My Sister's Keeper'. Reports suggest that production on this movie has been temporarily shut down.
Emilio Diaz appeared briefly in 'There's Something About Mary', in which his daughter starred.
According to US reports, Emilio Diaz, who was 58, recently picked up the flu, which later progressed to pneumonia.
Reports say that he died suddenly despite the fact that he had been in "terrific health" before his recent illness.
Diaz issued a statement saying: "My mom, sister and I are deeply appreciative of the overwhelming outpouring of love and support during this difficult time for us and all of our family."
"My dad was loved by so many people, and his humour and spirit will always live on in our hearts," she said.
Cameron Diaz is currently working on her new film 'My Sister's Keeper'. Reports suggest that production on this movie has been temporarily shut down.
Emilio Diaz appeared briefly in 'There's Something About Mary', in which his daughter starred.
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